What are the best Sicilian wines? Among the best Sicilian wines we can mention the wines obtained from native varieties such as Nero d’Avola, Nerello Mascalese, Frappato among the reds. While among the whites Catarratto, Grillo, Inzolia, Grecanico, Malvasia delle Lipari and Moscato d’Alessandria. Numerous wines are also produced from international grape varieties such as Chardonnay, Syrah, Merlot and Cabernet Sauvignon.